Co-writer and actor in Hungry Mile Theatre company's production of Citizen Gef.
2
Stiffness-dependent enhancement of inflammation was associated with increased expression of Rho activator, GEF-H1.
3
We show here that the Rho family GEF Vav2 plays a key role in this process.
4
The possible use of dominant negative ras-specific GEFs as a tool to down-regulate tumor growth is discussed.
5
These studies demonstrate that siRNAs are an ideal research tool for the assignment of Rho GEF function in vivo.
6
In this Review, we assess the association of GEFs and GAPs with cancer and their druggability for cancer therapeutics.
7
There was all party support for a motion to allow Ireland to join the Global Environmental Facility (GEF).
8
GEF is a funding mechanism for the UN convention on biological diversity and the UN framework convention on climate change.
9
Rho GTPase activity is temporally and spatially regulated by a set of specific guanine nucleotide exchange factors (GEFs).
10
Calculated GEF for the tested PAHs were similar in all cell lines and generally higher than the TEF usually used.
11
Arf activation is spatially and temporally regulated by distinct guanine nucleotide exchange factors (GEFs) at different Golgi compartments.
12
Inhibition of ECM crosslinking and stiffening by LOX suppression reduced EC inflammatory activation and GEF-H1 expression in response to LPS.
13
GEF activity was reduced from control values in extracts of heat-shocked cells and serum-deprived cells, concomitant with increased eIF-2 alpha phosphorylation.
14
The phenotype differs from that previously reported in families presenting FS or generalized epilepsy with febrile seizures plus (GEFS+).
15
These findings present a novel mechanism of stiffness-dependent exacerbation of vascular inflammation and escalation of ALI via stimulation of GEF-H1-Rho pathway.
16
Here we found that RINL has GEF activity for the Rab5 subfamily proteins by measuring their GTP-bound forms in cultured cells.